| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| We found that central administration of ghrelin increased both agouti related protein ( AGRP ) mRNA levels ( 245 . 8 + / 28 . 3 % of the saline treated controls ; p < 0 . 01 ) in the hypothalamus and food intake ( 5 . 7 + / 0 . 9 g ghrelin vs . 1 . 9 + / 0 . 5 g saline ; p < 0 . 05 ) . ^^^ Thus , ghrelin has an alternative role in stimulating food intake via an increase of AGRP rather than the release of GH from the pituitary . . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| After intracerebroventricular ghrelin administration , Fos protein , a marker of neuronal activation , was found in regions of primary importance in the regulation of feeding , including neuropeptide Y 6 ( NPY ) neurons and agouti related protein ( AGRP ) neurons . ^^^ Antibodies and antagonists of NPY and AGRP abolished ghrelin induced feeding . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| Recently , we showed that a single central administration of ghrelin increased food intake and hypothalamic agouti related protein ( AGRP ) gene expression in rodents , and the orexigenic effect of this peptide seems to be independent of its GH releasing activity . ^^^ We also found that chronic central administration of ghrelin increased both neuropeptide Y ( NPY ) mRNA levels ( 151 . 0 + / 10 . 1 % of saline treated controls ; P < 0 . 05 ) and AGRP mRNA levels ( 160 . 0 + / 22 . 5 % of saline treated controls ; P < 0 . 05 ) in the arcuate nucleus . ^^^ Thus , the primary hypothalamic targets of ghrelin are NPY / AGRP containing neurons , and ghrelin is a newly discovered orexigenic peptide in the brain and stomach . . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| Those agents include neuropeptide Y ( NPY ) , agouti related protein ( AGRP ) , melanocortin receptors ( MC R ) , cocaine amphetamine regulated transcript ( CART ) , pro opiomelanocortin ( POMC ) , orexin A and B ( hypocretins ) , melanin concentrating hormone ( MCH ) and ghrelin ( endogenous ligand of the growth hormone secretagogue receptor ) . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| Ghrelin activates growth hormone secretagogue receptor ( GHS R ) in hypothalamic ARC and stimulates growth hormone ( GH ) release and in vagal afferents to promote the expression and release of hypothalamic NPY and AgRP stimulating PVN and driving ingestive behaviour . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| Pharmacological evidence indicates that ghrelin ' s effects on food intake are mediated by neuropeptide Y ( NPY ) and agouti related protein ( AgRP ) in the central nervous system . ^^^ These include intracerebroventricular application of antibodies to neutralize NPY and AgRP , and the application of an NPY Y 1 receptor antagonist , which blocks some of the orexigenic effects of ghrelin . ^^^ Here we describe treatment of Agrp ( / ) ; Npy ( / ) and Mc3r ( / ) ; Mc4r ( / ) double knockout mice as well as Npy ( / ) and Agrp ( / ) single knockout mice with either ghrelin or an orally active nonpeptide ghrelin agonist . ^^^ The data demonstrate that NPY and AgRP are required for the orexigenic effects of ghrelin , as well as the involvement of the melanocortin pathway in ghrelin signaling . ^^^ Although deletion of either NPY or AgRP caused only a modest or nondetectable effect , ablation of both ligands completely abolished the orexigenic action of ghrelin . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| The novel peptide hormone is produced by gastric A like cells , and circulating levels rise before feeding , suggestive of ghrelin as an endogenous hunger factor . ghrelin stimulates food intake and promotes adiposity after peripheral or central administration , likely by activating hypothalamic neurons expressing the orexigenic neuropeptides neuropeptide Y ( NPY ) and agouti related protein ( AGRP ) . ^^^ To examine whether ghrelin induced feeding resembles NPY and AGRP [ AGRP fragment ( 83 132 ) ] induced orexia , we compared the short and long term orexigenic capacity of the three peptides . ^^^ In summary , ghrelin causes long term increases of food intake and , like AGRP , plays a previously unknown role as a suppressor of spontaneous physical activity . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| The actions of ghrelin and leptin appear to be mediated by the neuropeptide Y ( NPY ) and Agouti related protein ( AGRP ) system . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| Furthermore , ghrelin controls energy balance , enhancing fat mass deposition and food intake through the activation of the hypothalamic nuclei and the promotion of NPY ( neuropeptide Y ) and AGRP ( Agouti related protein ) expression ; since it stimulates weight gain , ghrelin is considered a possible important factor in the etiology of obesity . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| We will examine the involvement of the central melanocortin system in the incorporation of information from the adipostatic hormone leptin and acute hunger and satiety factors such as peptide YY ( PYY ( 3 36 ) ) and ghrelin via a neuronal network involving POMC / cocaine and amphetamine related transcript ( CART ) and neuropeptide Y ( NPY ) / AgRP neurons . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| Other orexigenic factors have been identified in teleost fish , including the agouti related protein ( AgRP ) and ghrelin . ^^^ In goldfish , nutritional status can modify the expression of mRNAs encoding a number of these peptides , which provides further evidence for their roles as appetite regulators : ( 1 ) brain mRNA expression of CCK , CART , tachykinins , galanin , ghrelin , and NPY undergo peri prandial variations ; and ( 2 ) fasting increases the brain mRNA expression of NPY , AgRP , and ghrelin as well as serum ghrelin levels , and decreases the brain mRNA expression of tachykinins , CART , and CCK . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| Several lines of evidence suggest that the orexigenic action of ghrelin is mediated through neuropeptide Y ( NPY ) / agouti related peptide ( AgRP ) neurones . ^^^ Because ADX reduces the orexigenic actions of NPY and AgRP , we hypothesised that ADX would also reduce the orexigenic action of ghrelin . ^^^ The results also suggest that , unlike the orexigenic effects of NPY and AgRP , the ability of ghrelin to stimulate food intake is maintained in ADX rats . . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| After ghrelin injection , AgRP mRNA expression in the hypothalamus was higher in + / + littermates than in GHR / mice , indicating a possible importance of AgRP in the GHR mediated effect of ghrelin . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| These lesions impaired responses to intracerebroventricular ( icv ) leptin ( 5 microg / 5 microl 10 d ) and ghrelin ( 2 microg / 5 microl ) , which are thought to alter feeding primarily by actions on ARC NPY / AGRP and proopiomelanocortin / cocaine and amphetamine related transcript neurons . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| Because ghrelin producing neurons are known to form synapses onto NPY / AgRP neurons , we suggest that the reversal of C 75 induced anorexia by ghrelin may be mediated by NPY / AgRP neurons . ^^^ These effects closely correlate with appropriate changes downstream in the expression of the hypothalamic neuropeptides that regulate feeding behavior , i . e . , down regulation of the expression of NPY and AgRP and up regulation of the expression of proopiomelanocortin / alpha melanocyte stimulating hormone , provoked by C 75 and reversed by ghrelin . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| The present studies tested whether methamphetamine alters the expression of neuropeptide Y ( NPY ) and agouti related peptide ( AgRP ) , two important orexigenic neuropeptides , or proopiomelanocortin ( POMC ) , the precursor for the anorexigenic peptide alpha melanocyte stimulating hormone , or the secretion of leptin , insulin and ghrelin , concomitant with inhibition of food intake . ^^^ In a separate study , AL and SF animals were killed just prior to expected food presentation , and expression of NPY , AgRP and POMC mRNAs in hypothalamus was determined using in situ hybridisation ; concentrations of leptin , insulin and ghrelin in serum were determined with radioimmunoassays . ^^^ In saline treated , SF controls , NPY and AgRP mRNA expression in arcuate nucleus and serum ghrelin were significantly elevated , and serum leptin and insulin were significantly reduced . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| Role of AgRP on Ghrelin induced feeding in the hypothalamic paraventricular nucleus . ^^^ To further investigate the role of the melanocortin system as mediator of ghrelin ' s orexigenic actions , we explored the involvement of AgRP in Ghrelin ' s orexigenic effect by testing the effect on food intake after their co administration in the PVN , during the light and dark phases of feeding in rats . ^^^ During both the phases of feeding , co administration of Ghrelin with either AgRP 50 or AgRP 100 pmol into the PVN did not produce a synergistic effect on the food intake , suggesting that ghrelin induction of feeding occurs by recruiting Agrp as one of the obligatory mediators of its orexigenic effect . . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| Exploration of the mechanism involved revealed significant downregulation of the orexigenic peptides : ghrelin in the stomach , and neuropeptide Y ( NPY ) but not Agouti related peptide ( AgRP ) in the hypothalamus , which was in line with the reduction in food intake in rats receiving EA stimulation as compared with those receiving restraint only . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| In six reviews , the melanocortins system ( including MC 4 and MC 3 receptors , Agrp , MSH ) , the NPY receptors ( including NPY Y 1 , NPY Y 2 , and NPY Y 5 , PYY 3 36 ) , the cannabinoid system ( including the development of rimonabant ) , the ghrelin ( GHS , growth hormone secretagogue ) system , the monoamine GPCRs ( including serotonin , adrenergic and histamine receptors ) , orexin ( hypocretin ) system and the galanin receptors are covered . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| Ghrelin stimulates the synthesis of neuropeptide Y ( NPY ) and agouti related protein ( AgRP ) in the arcuate nucleus neurons of the hypothalamus and hindbrain , which in turn enhance food intake . ^^^ Ghrelin expressing neurons modulate the action of both orexigenic NPY / AgRP and anorexigenic pro opiomelanocortin neurons . ^^^ AMP activated protein kinase is activated by ghrelin in the hypothalamus , which contributes to lower intracellular long chain fatty acids , and this appears to be the molecular signal for the expression of NPY and AgRP . ^^^ |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O00253 and Q9UBU3 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| Those agents include neuropeptide Y ( NPY ) , agouti related protein ( AGRP ) , melanocortin receptors ( MC R ) , cocaine amphetamine regulated transcript ( CART ) , pro opiomelanocortin ( POMC ) , orexin A and B ( hypocretins ) , melanin concentrating hormone ( MCH ) and ghrelin ( endogenous ligand of the growth hormone secretagogue receptor ) . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| In six reviews , the melanocortins system ( including MC 4 and MC 3 receptors , Agrp , MSH ) , the NPY receptors ( including NPY Y 1 , NPY Y 2 , and NPY Y 5 , PYY 3 36 ) , the cannabinoid system ( including the development of rimonabant ) , the ghrelin ( GHS , growth hormone secretagogue ) system , the monoamine GPCRs ( including serotonin , adrenergic and histamine receptors ) , orexin ( hypocretin ) system and the galanin receptors are covered . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| We found that central administration of ghrelin increased both agouti related protein ( AGRP ) mRNA levels ( 245 . 8 + / 28 . 3 % of the saline treated controls ; p < 0 . 01 ) in the hypothalamus and food intake ( 5 . 7 + / 0 . 9 g ghrelin vs . 1 . 9 + / 0 . 5 g saline ; p < 0 . 05 ) . ^^^ Thus , ghrelin has an alternative role in stimulating food intake via an increase of AGRP rather than the release of GH from the pituitary . . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| After intracerebroventricular ghrelin administration , Fos protein , a marker of neuronal activation , was found in regions of primary importance in the regulation of feeding , including neuropeptide Y 6 ( NPY ) neurons and agouti related protein ( AGRP ) neurons . ^^^ Antibodies and antagonists of NPY and AGRP abolished ghrelin induced feeding . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| Furthermore , ghrelin controls energy balance , enhancing fat mass deposition and food intake through the activation of the hypothalamic nuclei and the promotion of NPY ( neuropeptide Y ) and AGRP ( Agouti related protein ) expression ; since it stimulates weight gain , ghrelin is considered a possible important factor in the etiology of obesity . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| We will examine the involvement of the central melanocortin system in the incorporation of information from the adipostatic hormone leptin and acute hunger and satiety factors such as peptide YY ( PYY ( 3 36 ) ) and ghrelin via a neuronal network involving POMC / cocaine and amphetamine related transcript ( CART ) and neuropeptide Y ( NPY ) / AgRP neurons . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| Ghrelin activates growth hormone secretagogue receptor ( GHS R ) in hypothalamic ARC and stimulates growth hormone ( GH ) release and in vagal afferents to promote the expression and release of hypothalamic NPY and AgRP stimulating PVN and driving ingestive behaviour . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| Pharmacological evidence indicates that ghrelin ' s effects on food intake are mediated by neuropeptide Y ( NPY ) and agouti related protein ( AgRP ) in the central nervous system . ^^^ These include intracerebroventricular application of antibodies to neutralize NPY and AgRP , and the application of an NPY Y 1 receptor antagonist , which blocks some of the orexigenic effects of ghrelin . ^^^ Here we describe treatment of Agrp ( / ) ; Npy ( / ) and Mc3r ( / ) ; Mc4r ( / ) double knockout mice as well as Npy ( / ) and Agrp ( / ) single knockout mice with either ghrelin or an orally active nonpeptide ghrelin agonist . ^^^ The data demonstrate that NPY and AgRP are required for the orexigenic effects of ghrelin , as well as the involvement of the melanocortin pathway in ghrelin signaling . ^^^ Although deletion of either NPY or AgRP caused only a modest or nondetectable effect , ablation of both ligands completely abolished the orexigenic action of ghrelin . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| Recently , we showed that a single central administration of ghrelin increased food intake and hypothalamic agouti related protein ( AGRP ) gene expression in rodents , and the orexigenic effect of this peptide seems to be independent of its GH releasing activity . ^^^ We also found that chronic central administration of ghrelin increased both neuropeptide Y ( NPY ) mRNA levels ( 151 . 0 + / 10 . 1 % of saline treated controls ; P < 0 . 05 ) and AGRP mRNA levels ( 160 . 0 + / 22 . 5 % of saline treated controls ; P < 0 . 05 ) in the arcuate nucleus . ^^^ Thus , the primary hypothalamic targets of ghrelin are NPY / AGRP containing neurons , and ghrelin is a newly discovered orexigenic peptide in the brain and stomach . . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| These lesions impaired responses to intracerebroventricular ( icv ) leptin ( 5 microg / 5 microl 10 d ) and ghrelin ( 2 microg / 5 microl ) , which are thought to alter feeding primarily by actions on ARC NPY / AGRP and proopiomelanocortin / cocaine and amphetamine related transcript neurons . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| Because ghrelin producing neurons are known to form synapses onto NPY / AgRP neurons , we suggest that the reversal of C 75 induced anorexia by ghrelin may be mediated by NPY / AgRP neurons . ^^^ These effects closely correlate with appropriate changes downstream in the expression of the hypothalamic neuropeptides that regulate feeding behavior , i . e . , down regulation of the expression of NPY and AgRP and up regulation of the expression of proopiomelanocortin / alpha melanocyte stimulating hormone , provoked by C 75 and reversed by ghrelin . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| The present studies tested whether methamphetamine alters the expression of neuropeptide Y ( NPY ) and agouti related peptide ( AgRP ) , two important orexigenic neuropeptides , or proopiomelanocortin ( POMC ) , the precursor for the anorexigenic peptide alpha melanocyte stimulating hormone , or the secretion of leptin , insulin and ghrelin , concomitant with inhibition of food intake . ^^^ In a separate study , AL and SF animals were killed just prior to expected food presentation , and expression of NPY , AgRP and POMC mRNAs in hypothalamus was determined using in situ hybridisation ; concentrations of leptin , insulin and ghrelin in serum were determined with radioimmunoassays . ^^^ In saline treated , SF controls , NPY and AgRP mRNA expression in arcuate nucleus and serum ghrelin were significantly elevated , and serum leptin and insulin were significantly reduced . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| The novel peptide hormone is produced by gastric A like cells , and circulating levels rise before feeding , suggestive of ghrelin as an endogenous hunger factor . ghrelin stimulates food intake and promotes adiposity after peripheral or central administration , likely by activating hypothalamic neurons expressing the orexigenic neuropeptides neuropeptide Y ( NPY ) and agouti related protein ( AGRP ) . ^^^ To examine whether ghrelin induced feeding resembles NPY and AGRP [ AGRP fragment ( 83 132 ) ] induced orexia , we compared the short and long term orexigenic capacity of the three peptides . ^^^ In summary , ghrelin causes long term increases of food intake and , like AGRP , plays a previously unknown role as a suppressor of spontaneous physical activity . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| The actions of ghrelin and leptin appear to be mediated by the neuropeptide Y ( NPY ) and Agouti related protein ( AGRP ) system . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| Ghrelin stimulates the synthesis of neuropeptide Y ( NPY ) and agouti related protein ( AgRP ) in the arcuate nucleus neurons of the hypothalamus and hindbrain , which in turn enhance food intake . ^^^ Ghrelin expressing neurons modulate the action of both orexigenic NPY / AgRP and anorexigenic pro opiomelanocortin neurons . ^^^ AMP activated protein kinase is activated by ghrelin in the hypothalamus , which contributes to lower intracellular long chain fatty acids , and this appears to be the molecular signal for the expression of NPY and AgRP . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| Other orexigenic factors have been identified in teleost fish , including the agouti related protein ( AgRP ) and ghrelin . ^^^ In goldfish , nutritional status can modify the expression of mRNAs encoding a number of these peptides , which provides further evidence for their roles as appetite regulators : ( 1 ) brain mRNA expression of CCK , CART , tachykinins , galanin , ghrelin , and NPY undergo peri prandial variations ; and ( 2 ) fasting increases the brain mRNA expression of NPY , AgRP , and ghrelin as well as serum ghrelin levels , and decreases the brain mRNA expression of tachykinins , CART , and CCK . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| Several lines of evidence suggest that the orexigenic action of ghrelin is mediated through neuropeptide Y ( NPY ) / agouti related peptide ( AgRP ) neurones . ^^^ Because ADX reduces the orexigenic actions of NPY and AgRP , we hypothesised that ADX would also reduce the orexigenic action of ghrelin . ^^^ The results also suggest that , unlike the orexigenic effects of NPY and AgRP , the ability of ghrelin to stimulate food intake is maintained in ADX rats . . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| After ghrelin injection , AgRP mRNA expression in the hypothalamus was higher in + / + littermates than in GHR / mice , indicating a possible importance of AgRP in the GHR mediated effect of ghrelin . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| Role of AgRP on Ghrelin induced feeding in the hypothalamic paraventricular nucleus . ^^^ To further investigate the role of the melanocortin system as mediator of ghrelin ' s orexigenic actions , we explored the involvement of AgRP in Ghrelin ' s orexigenic effect by testing the effect on food intake after their co administration in the PVN , during the light and dark phases of feeding in rats . ^^^ During both the phases of feeding , co administration of Ghrelin with either AgRP 50 or AgRP 100 pmol into the PVN did not produce a synergistic effect on the food intake , suggesting that ghrelin induction of feeding occurs by recruiting Agrp as one of the obligatory mediators of its orexigenic effect . . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| Exploration of the mechanism involved revealed significant downregulation of the orexigenic peptides : ghrelin in the stomach , and neuropeptide Y ( NPY ) but not Agouti related peptide ( AgRP ) in the hypothalamus , which was in line with the reduction in food intake in rats receiving EA stimulation as compared with those receiving restraint only . ^^^ |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9UBU3 and O00253 |
Pubmed |
SVM Score :0.0 |
| NA |
|