Navigator

Visualize your graph using versatile graphics, powered with OpenGL accelerated libraries.

Load and visualize thousands of relationships and interactions with powerful multi-threaded algorithms.

View networks in 2D and 3D. Position nodes using a mixture of automatic force-directed layout.

Use 3D views with various node shapes and edge styles to convey important information from large complex networks.

Use analysis tools like Shortest Paths with built-in spreadsheets to highlight areas of interest.

Use the innovative Hotbox pop-up tool to quickly perform the most common network operations.

Subsets can be used to models complexes/hubs and collapsed into single nodes for a higher level abstraction of the data

Screen-capture showing nodes on a circular layout, with hub nodes automatically scaled according to their degree (connectivity).

The scalability of NAViGaTOR is demonstrated by rendering an extremely large network (1.7 million edges; see ‘MouseNet’, Table 3.1) in under 20 minutes. Automated filters were used to color nodes by degree.

Circular and linear layouts are shown for a model network, along with both curved and bent edges. We are currently experimenting with curved edges to identify an optimal interface for users to manipulate complex curves in the networks.

A combination of layouts and edge styles is used to illustrate the presence of highly connected hubs in a 3-dimensional rendering of this model network.

Savas, S., Geraci, J., Jurisica, I., Liu, G. A comprehensive catalogue of functional genetic variations in the EGFR pathway: Protein-protein interaction analysis reveals novel genes and polymorphisms important for cancer research. Int J Cancer,125(6): 1257-65, 2009.

Savas, S., Geraci, J., Jurisica, I., Liu, G. A comprehensive catalogue of functional genetic variations in the EGFR pathway: Protein-protein interaction analysis reveals novel genes and polymorphisms important for cancer research. Int J Cancer,125(6): 1257-65, 2009.

Showing data from Cell paper, Fig 5 Global Sequencing of Proteolytic Cleavage Sites in Apoptosis by Specific Labeling of Protein N Termini

Cox, B., Kotlyar, M., Evangelou, A., Ignatchenko, V., Ignatchenko, A., Whiteley, K., Jurisica, I., Adamson, L., Rossant, J., Kislinger, T., Comparative systems biology of human and mouse as a tool for modeling human placental pathology, Mol Sys Bio, 5, 279, 2009.

Agarwal R., Jurisica, I., Cheng K.W., Mills G.B. The emerging role of the Rab25 small GTPase in cancer, Traffic, 2009. E-Pub July 23, 2009. In Press.