| Interacting proteins: Q9UER7 and Q92769 |
Pubmed |
SVM Score :1.285234 |
| Using co fractionation and co immunoprecipitation we demonstrate that hDaxx associates with proteins that are critical for transcriptional repression , such as histone deacetylase 2 , constituents of chromatin such as core histones H2A , H2B , H 3 and H 4 , and Dek , a chromatin associated protein reported to change the topology of DNA in chromatin in vitro . 1.285234^^^ |
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| Interacting proteins: Q9UER7 and Q92769 |
Pubmed |
SVM Score :0.0 |
| Temporal analysis of IE 1 distribution revealed its initial segregation into ND 10 by binding to PML and / or Daxx and IE 1 dependent recruitment of the transcriptional repressor histone deacetylase 2 ( HDAC 2 ) to this site . ^^^ However , these protein aggregates are dissociated in cells producing sufficient IE 1 through titration of PML , Daxx , and HDAC 2 . ^^^ |
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| Interacting proteins: Q9UER7 and Q92769 |
Pubmed |
SVM Score :0.0 |
| Furthermore , we demonstrated an interaction of SUMO 1 modified CBP with the transcriptional corepressor Daxx and an essential role of Daxx in mediating SUMO dependent transcriptional regulation of CBP through histone deacetylase 2 recruitment . ^^^ |
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