| Interacting proteins: Q13330 and Q92769 |
Pubmed |
SVM Score :0.0 |
| The same regions of the protein that are required for repression physically interact with components of chromatin remodeling complexes , HDAC 1 , HDAC 2 , RbAp46 / 48 , MTA 1 , and MTA 2 . ^^^ |
|
| Interacting proteins: Q13330 and Q92769 |
Pubmed |
SVM Score :0.0 |
| Co immunoprecipitation and chromatin immunoprecipitation assay experiments revealed histone deacetylase 2 ( HDAC 2 ) MTA 1 protein protein interactions and the MTA 1 dependent recruitment of HDAC 2 to the distal MMP 9 promoter region , yielding diminished histone H3 / H4 acetylation . ^^^ However , HDAC 2 binding and H3 / H4 acetylation at the proximal MMP 9 region were unaffected by MTA 1 expression . ^^^ |
|
| Interacting proteins: Q13330 and Q92769 |
Pubmed |
SVM Score :0.0 |
| MTA 1 deregulation in breast cancer cells led to its interactions with the CAK complex components , ER , and HDAC 2 . ^^^ |
|
| Interacting proteins: Q13330 and Q92769 |
Pubmed |
SVM Score :0.0 |
| In glutathione S transferase pull down assays , MBD3L2 is found associated with several known components of the Mi 2 NuRD complex , including HDAC 1 , HDAC 2 , MTA 1 , MBD 3 , p 66 , RbAp 46 , and RbAp 48 . ^^^ |
|
| Interacting proteins: Q13330 and Q92769 |
Pubmed |
SVM Score :0.0 |
| In human colorectal tissue samples , the gene expressions of 4 coactivators , p 300 , pCAF , TIF 2 and TRAP 220 , and 7 corepressors , N CoR , REA , MTA 1 , MTA1L1 , HDAC 1 , HDAC 2 and HDAC 3 , linked to estrogen receptors ( ER ) , were revealed by traditional RT PCR . ^^^ The decline of mRNA levels of all coactivators and the increase of NCoR , HDAC 1 , HDAC 2 and MTA 1 were observed from normal to tumor tissue , whereas REA , HDAC 3 and MTA1L1 expressions were similar in both tissue compartments . ^^^ |
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| Interacting proteins: Q13330 and Q92769 |
Pubmed |
SVM Score :0.0 |
| Four components of the MeCP 1 transcriptional repression complex were identified : MBD 2 , RBAP 48 , HDAC 2 , and MTA 1 . ^^^ |
|
| Interacting proteins: Q13330 and Q92769 |
Pubmed |
SVM Score :0.0 |
| NA |
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