Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
GR acts as a direct inhibitor of NF kappa B induced HAT activity and also by recruiting HDAC 2 to the NF kappa B / HAT complex . ^^^
Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
HDAC 2 and NF kappa B p 65 co immunoprecipitated from mesangial cell nuclear extracts , and in vitro translated HDAC 2 specifically interacted with an NF kappa B p 65 GST fusion protein . ^^^ The specific recruitment of HDAC 2 to NF kappa B at target promoters and the consequent effects on acetylation status may play an important role in regulating iNOS as well as other NF kappa B dependent genes involved in inflammation . . ^^^
Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
Ebp 1 bound HDAC 2 , but not HDAC 1 , in vitro . ^^^
Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
We show here that IkappaBalpha enhances the transactivation potential of several homeodomain containing proteins such as HOXB 7 and Pit 1 through a NF kappaB independent association with histone deacetylase ( HDAC ) 1 and HDAC 3 but not with HDAC 2 , 4 , 5 , and 6 . ^^^
Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
Ebp 1 bound E2F consensus oligonucleotides in association with E2F1 , retinoblastoma protein , and HDAC 2 . ^^^
Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
In this study , we investigated recruitment of coactivators ( SRC 1 , SRC 2 , and SRC 3 ) and corepressors ( HDAC 1 , HDAC 2 , HDAC 3 , SMRT , and NCoR ) to the IkappaB alpha gene promoter after NF kappaB activation by tumor necrosis factor alpha . ^^^
Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
Recombinant Sin3A bound Ebp 1 directly , but recombinant HDAC 2 failed to bind Ebp 1 . ^^^
Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
Loss of HDAC 2 did not reduce GR nuclear translocation , GR binding to glucocorticoid response element ( GRE ) on DNA , or GR induced DNA or gene induction but inhibited the association between GR and NF kappaB . ^^^ GR becomes acetylated after ligand binding , and HDAC 2 mediated GR deacetylation enables GR binding to the NF kappaB complex . ^^^ Thus , reduction of HDAC 2 plays a critical role in glucocorticoid insensitivity in repressing NF kappaB mediated , but not GRE mediated , gene expression . . ^^^
Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
Furthermore , apicidin activation of NF kappaB seems to result from HDAC 1 inhibition , as evidenced by the observation that overexpression of HDAC 1 , but not HDAC 2 , 3 or 4 , dramatically inhibits NF kappaB reporter gene activity . ^^^
Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
The p 65 ( RelA ) subunit of NF kappaB interacts with the histone deacetylase ( HDAC ) corepressors HDAC 1 and HDAC 2 to negatively regulate gene expression . ^^^ Expression of HDAC 1 and HDAC 2 repressed tumor necrosis factor ( TNF ) induced NF kappaB dependent gene expression . ^^^ Consistent with this , we show that HDAC 1 and HDAC 2 target NF kappaB through a direct association of HDAC 1 with the Rel homology domain of p 65 . ^^^ HDAC 2 does not interact with NF kappaB directly but can regulate NF kappaB activity through its association with HDAC 1 . ^^^ Moreover , it suggests that the association of NF kappaB with the HDAC 1 and HDAC 2 corepressor proteins functions to repress expression of NF kappaB regulated genes as well as to control the induced level of expression of these genes . . ^^^
Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
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Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
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Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
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Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
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Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
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Interacting proteins: Q92769 and P19838	Pubmed	SVM Score :0.0
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