| Interacting proteins: P19784 and Q92769 |
Pubmed |
SVM Score :0.0 |
| We demonstrated that Sp 1 and Sp 3 recruit HDAC 1 and HDAC 2 , with the latter being phosphorylated by protein kinase CK 2 . ^^^ |
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| Interacting proteins: P19784 and Q92769 |
Pubmed |
SVM Score :0.0 |
| Regulation of histone deacetylase 2 by protein kinase CK 2 . ^^^ However , unlike HDAC 1 , which can be phosphorylated by protein kinase CK 2 , cAMP dependent protein kinase , and protein kinase G , HDAC 2 is phosphorylated uniquely by protein kinase CK 2 in vitro . ^^^ Studies using unfractionated cell extracts with CK 2 inhibitors suggest that protein kinase CK 2 is the major source of HDAC 2 kinase . ^^^ |
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| Interacting proteins: P19784 and Q92769 |
Pubmed |
SVM Score :0.0 |
| The transcriptional repressor Sp 3 is associated with CK 2 phosphorylated histone deacetylase 2 . ^^^ We show that protein kinase CK 2 is associated with and phosphorylates HDAC 2 . ^^^ CK 2 phosphorylation of HDAC 2 recruited by Sp 1 or Sp 3 could regulate HDAC activity and alter the balance of histone deacetylase and histone acetyltransferase activities and dynamic chromatin remodeling of estrogen regulated genes . . ^^^ |
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| Interacting proteins: P19784 and Q92769 |
Pubmed |
SVM Score :0.0 |
| NA |
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