| Interacting proteins: Q92769 and P06400 |
Pubmed |
SVM Score :0.0 |
| Unlike the other maize deacetylases , HD1A and nucleolar HD 2 , HD1B copurified as a complex with a protein related to the retinoblastoma associated protein , Rbap 46 . ^^^ |
|
| Interacting proteins: Q92769 and P06400 |
Pubmed |
SVM Score :0.0 |
| The failure to deacetylate and thus repress transcription by the Class 1 histone deacetylases HDAC 1 and HDAC 2 due to disruption of the Rb family of proteins has been firmly established as a mechanism leading to increases in growth rate and cellular proliferation . ^^^ |
|
| Interacting proteins: Q92769 and P06400 |
Pubmed |
SVM Score :0.0 |
| Repression by Rb is mediated , at least in part , by a histone deacetylase complex , whose enzymatic activity relies on HDAC 1 , HDAC 2 or HDAC 3 . ^^^ Recently , we have shown that the Rb associated histone deacetylase complex contains RbAp 48 protein , which interacts with HDAC 1 and HDAC 2 . ^^^ Taken together , our data suggest a model in which Rb mediates the recruitment to E2F regulating promoters of a repressive complex containing either HDAC 1 , HDAC 2 or HDAC 3 and the histone binding protein RbAp48 . . ^^^ |
|
| Interacting proteins: Q92769 and P06400 |
Pubmed |
SVM Score :0.0 |
| Consistent with this interpretation , the N terminal transcriptional repression domain of Suv39H1 bound the so called ' core histone deacetylase complex ' , composed of HDAC 1 , HDAC 2 and the Rb associated proteins RbAp 48 and RbAp 46 . ^^^ |
|
| Interacting proteins: Q92769 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92769 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92769 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92769 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q92769 and P06400 |
Pubmed |
SVM Score :0.0 |
| NA |
|