Interacting proteins: Q16576 and Q13547 |
Pubmed |
SVM Score :0.0 |
Here , we identify SAP 30 as a novel component of the human histone deacetylase complex that includes Sin 3 , the histone deacetylases HDAC 1 and HDAC 2 , histone binding proteins RbAp 46 and RbAp 48 , as well as other polypeptides . ^^^ |
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Interacting proteins: Q16576 and Q13547 |
Pubmed |
SVM Score :0.0 |
The histone deacetylases HDAC 1 and HDAC 2 and the histone binding proteins RbAp 48 and RbAp 46 form a core complex shared between NuRD and Sin 3 histone deacetylase complexes . ^^^ |
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Interacting proteins: Q16576 and Q13547 |
Pubmed |
SVM Score :0.0 |
We have previously found that a human Sin 3 HDAC complex includes HDAC 1 and HDAC 2 , the histone binding proteins RbAp 46 and RbAp 48 , and two novel polypeptides SAP 30 and SAP 18 . ^^^ |
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Interacting proteins: Q16576 and Q13547 |
Pubmed |
SVM Score :0.0 |
Consistent with this interpretation , the N terminal transcriptional repression domain of Suv39H1 bound the so called ' core histone deacetylase complex ' , composed of HDAC 1 , HDAC 2 and the Rb associated proteins RbAp 48 and RbAp 46 . ^^^ |
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Interacting proteins: Q16576 and Q13547 |
Pubmed |
SVM Score :0.0 |
NuRD complex , including HDAC 1 , HDAC 2 , MTA 2 , MBD 2 , RbAp 46 , and RbAp 48 , but MBD 3 is not found in the MBD3L1 bound fraction . ^^^ |
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Interacting proteins: Q16576 and Q13547 |
Pubmed |
SVM Score :0.0 |
In glutathione S transferase pull down assays , MBD3L2 is found associated with several known components of the Mi 2 NuRD complex , including HDAC 1 , HDAC 2 , MTA 1 , MBD 3 , p 66 , RbAp 46 , and RbAp 48 . ^^^ |
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Interacting proteins: Q16576 and Q13547 |
Pubmed |
SVM Score :0.0 |
The Mi 2 / NuRD components MBD 3 , RbAp 46 , RbAp 48 , and HDAC 1 were found to bind to both p66alpha and p66beta in vivo . ^^^ HDAC 1 binding to p66alpha was lost in the case of a p66alphaK30R mutant , and RbAp 46 binding was reduced in the case of a p66betaK33R mutant . ^^^ |
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Interacting proteins: Q16576 and Q13547 |
Pubmed |
SVM Score :0.0 |
NA |
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Interacting proteins: Q16576 and Q13547 |
Pubmed |
SVM Score :0.0 |
NA |
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