| Interacting proteins: Q13330 and Q13547 |
Pubmed |
SVM Score :0.65019515 |
| Coimmunoprecipitation of myc tagged MTA 1 and FLAG tagged histone deacetylase 1 ( HDAC 1 ) , followed by western blot analysis using anti myc and anti FLAG monoclonal antibodies showed that MTA 1 physically bound with HDAC 1 in COS 7 cells . 0.65019515^^^ |
|
| Interacting proteins: Q13330 and Q13547 |
Pubmed |
SVM Score :0.0 |
| Other members of the NRD complex , HDAC 1 , MTA 1 , and MTA 2 , are also detectable in ATR immunoprecipitates . ^^^ |
|
| Interacting proteins: Q13330 and Q13547 |
Pubmed |
SVM Score :0.0 |
| Furthermore , MTA 1 directly interacts with histone deacetylase 1 and 2 and with the activation domain of ER alpha . ^^^ |
|
| Interacting proteins: Q13330 and Q13547 |
Pubmed |
SVM Score :0.0 |
| The same regions of the protein that are required for repression physically interact with components of chromatin remodeling complexes , HDAC 1 , HDAC 2 , RbAp46 / 48 , MTA 1 , and MTA 2 . ^^^ |
|
| Interacting proteins: Q13330 and Q13547 |
Pubmed |
SVM Score :0.0 |
| In glutathione S transferase pull down assays , MBD3L2 is found associated with several known components of the Mi 2 NuRD complex , including HDAC 1 , HDAC 2 , MTA 1 , MBD 3 , p 66 , RbAp 46 , and RbAp 48 . ^^^ |
|
| Interacting proteins: Q13330 and Q13547 |
Pubmed |
SVM Score :0.0 |
| In human colorectal tissue samples , the gene expressions of 4 coactivators , p 300 , pCAF , TIF 2 and TRAP 220 , and 7 corepressors , N CoR , REA , MTA 1 , MTA1L1 , HDAC 1 , HDAC 2 and HDAC 3 , linked to estrogen receptors ( ER ) , were revealed by traditional RT PCR . ^^^ The decline of mRNA levels of all coactivators and the increase of NCoR , HDAC 1 , HDAC 2 and MTA 1 were observed from normal to tumor tissue , whereas REA , HDAC 3 and MTA1L1 expressions were similar in both tissue compartments . ^^^ |
|
| Interacting proteins: Q13330 and Q13547 |
Pubmed |
SVM Score :0.0 |
| MTA 1 induced the deacetylation of HIF 1alpha by increasing the expression of histone deacetylase 1 ( HDAC 1 ) . ^^^ Collectively , our data provide evidence of a positive cross talk between HIF 1alpha and MTA 1 , which is mediated by HDAC 1 recruitment , and indicate a close connection between MTA 1 associated metastasis and HIF 1 induced tumor angiogenesis . . ^^^ |
|
| Interacting proteins: Q13330 and Q13547 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13330 and Q13547 |
Pubmed |
SVM Score :0.0 |
| NA |
|