| Interacting proteins: Q06455 and Q13547 |
Pubmed |
SVM Score :0.0 |
| Previously , we demonstrated that the ETO moiety recruits a transcription repression complex that includes the histone deacetylase ( HDAC 1 ) enzyme . ^^^ Here , we used inhibitors of HDAC 1 to study the pathophysiology of AML 1 ETO . ^^^ |
|
| Interacting proteins: Q06455 and Q13547 |
Pubmed |
SVM Score :0.0 |
| In addition , of eight histone deacetylases ( HDACs ) tested , only the class 1 HDACs HDAC 1 , HDAC 2 , and HDAC 3 bind ETO . ^^^ Furthermore , ETO 2 binds HDAC 1 , HDAC 2 , and HDAC 3 but also interacts with HDAC 6 and HDAC 8 . ^^^ |
|
| Interacting proteins: Q06455 and Q13547 |
Pubmed |
SVM Score :0.0 |
| The ETO moiety was shown to interact with the nuclear receptor co repressor ( N CoR ) complex , which includes mSin3A and the histone deacetylase , HDAC 1 . ^^^ |
|
| Interacting proteins: Q06455 and Q13547 |
Pubmed |
SVM Score :0.0 |
| The Nervy homology 2 ( NHR 2 ) domain in ETO mediates oligomerization and AML1 / ETO ' s interactions with ETO , MTGR 1 , and MTG 16 , and with the corepressor molecules mSin3A and HDAC 1 and HDAC 3 . ^^^ |
|
| Interacting proteins: Q06455 and Q13547 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06455 and Q13547 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06455 and Q13547 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q06455 and Q13547 |
Pubmed |
SVM Score :0.0 |
| NA |
|