RFX 5 specifically interacts with histone deacetylase 2 ( HDAC 2 ) and the mammalian transcriptional repressor ( mSin3B ) , whereas RFX 1 preferably interacts with HDAC 1 and mSin3A . 0.62696325^^^ RFX 1 binds to the methylated collagen sequence with much higher affinity than unmethylated sequence , recruiting more HDAC 1 and mSin3A . 0.57526041^^^