| Interacting proteins: Q12824 and P01106 |
Pubmed |
SVM Score :0.0 |
| Codons 152 and 299 of SMARCB 1 are localized near or within the binding site for the cMYC protein . ^^^ The amount of immunoprecipitated cMYC protein was reduced in two different cell lines expressing the codon 152 polymorphic SMARCB 1 clone compared with those expressing wild type SMARCB 1 , regardless of the identical expression of SMARCB 1 protein in both cell lines . ^^^ Therefore , the SNP at codon 152 is considered to be one of the coding SNPs that alters the SMARCB 1 cMYC complex , which regulates various tumor suppressor related genes against cancer . ^^^ We found a nucleotide change at codon 152 of SMARCB 1 that may alter the amount of immunoprecipitated cMYC protein , but we finally determined that SMARCB 1 is highly conserved in human solid carcinomas . . ^^^ |
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| Interacting proteins: Q12824 and P01106 |
Pubmed |
SVM Score :0.0 |
| Furthermore , ORC 1 inhibited E box dependent transcription activity of c Myc by competitive binding to the C terminal region of c Myc with SNF 5 , a component of chromatin remodelling complex SNF / Swi1 . ^^^ |
|
| Interacting proteins: Q12824 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12824 and P01106 |
Pubmed |
SVM Score :0.0 |
| NA |
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