| Among 31 PTPs tested , T cell ( TC ) PTP , PTP beta , PTP1B , stomach cancer associated PTP 1 ( SAP 1 ) , Pyst 2 , Meg 2 , and PTP H 1 showed specificity for phosphorylated GHR that had been produced by coexpression with a kinase in bacteria . ^^^ In this assay , only TC PTP , PTP1B , PTP H 1 , and SAP 1 interacted with the mature form of the phosphorylated GHR . ^^^ Finally , mRNA tissue distribution of these PTPs by RT PCR analysis and coexpression of the wild type PTPs to test their ability to dephosphorylate ligand activated GHR suggest PTP H 1 and PTP1B as potential candidates involved in GHR signaling . . ^^^ |