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B4E1C1: cDNA FLJ55943, highly similar to Death domain-associated protein 6 {ECO:0000313|EMBL:BAG64733.1}
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O00220: Tumor necrosis factor receptor superfamily member 10A; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; CD261; Precursor
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O00303: Eukaryotic translation initiation factor 3 subunit F {ECO:0000255|HAMAP-Rule:MF_03005}; eIF3f {ECO:0000255|HAMAP-Rule:MF_03005}; Deubiquitinating enzyme eIF3f; 3.4.19.12; Eukaryotic translation initiation factor 3 subunit 5 {ECO:0000255|HAMAP-Rule:MF_03005}; eIF-3-epsilon {ECO:0000255|HAMAP-Rule:MF_03005}; eIF3 p47 {ECO:0000255|HAMAP-Rule:MF_03005}
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O14733: Dual specificity mitogen-activated protein kinase kinase 7; MAP kinase kinase 7; MAPKK 7; 2.7.12.2; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; Stress-activated protein kinase kinase 4; SAPK kinase 4; SAPKK-4; SAPKK4; c-Jun N-terminal kinase kinase 2; JNK kinase 2; JNKK 2
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Pubmed References:
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O14763: Tumor necrosis factor receptor superfamily member 10B; Death receptor 5; TNF-related apoptosis-inducing ligand receptor 2; TRAIL receptor 2; TRAIL-R2; CD262; Precursor
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O14920: Inhibitor of nuclear factor kappa-B kinase subunit beta; I-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; 2.7.11.10; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB
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Pubmed References:
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O15519: CASP8 and FADD-like apoptosis regulator; Caspase homolog; CASH; Caspase-eight-related protein; Casper; Caspase-like apoptosis regulatory protein; CLARP; Cellular FLICE-like inhibitory protein; c-FLIP; FADD-like antiapoptotic molecule 1; FLAME-1; Inhibitor of FLICE; I-FLICE; MACH-related inducer of toxicity; MRIT; Usurpin; CASP8 and FADD-like apoptosis regulator subunit p43; CASP8 and FADD-like apoptosis regulator subunit p12; Precursor
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Pubmed References:
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O43353: Receptor-interacting serine/threonine-protein kinase 2; 2.7.11.1; CARD-containing interleukin-1 beta-converting enzyme-associated kinase; CARD-containing IL-1 beta ICE-kinase; RIP-like-interacting CLARP kinase; Receptor-interacting protein 2; RIP-2; Tyrosine-protein kinase RIPK2; 2.7.10.2
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Pubmed References:
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O60496: Docking protein 2; Downstream of tyrosine kinase 2; p56(dok-2)
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Pubmed References:
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O60936: Nucleolar protein 3; Apoptosis repressor with CARD; Muscle-enriched cytoplasmic protein; Myp; Nucleolar protein of 30 kDa; Nop30
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Pubmed References:
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O75533: Splicing factor 3B subunit 1; Pre-mRNA-splicing factor SF3b 155 kDa subunit; SF3b155; Spliceosome-associated protein 155; SAP 155
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O75618: Death effector domain-containing protein; DEDPro1; Death effector domain-containing testicular molecule; FLDED-1
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Pubmed References:
1
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P04049: RAF proto-oncogene serine/threonine-protein kinase; 2.7.11.1; Proto-oncogene c-RAF; cRaf; Raf-1
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Pubmed References:
1
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P04637: Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53
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Pubmed References:
1
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P06396: Gelsolin; AGEL; Actin-depolymerizing factor; ADF; Brevin; Precursor
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Pubmed References:
1
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P07900: Heat shock protein HSP 90-alpha; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38
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Pubmed References:
1
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P0CG48: Polyubiquitin-C; Ubiquitin; Precursor
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Pubmed References:
1
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P12956: X-ray repair cross-complementing protein 6; 3.6.4.-; 4.2.99.-; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 6
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Pubmed References:
1
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P14174: Macrophage migration inhibitory factor; MIF; 5.3.2.1; Glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase; 5.3.3.12; Phenylpyruvate tautomerase
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Pubmed References:
1
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P14866: Heterogeneous nuclear ribonucleoprotein L; hnRNP L
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Pubmed References:
1
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P19838: Nuclear factor NF-kappa-B p105 subunit; DNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; Nuclear factor NF-kappa-B p50 subunit
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P20963: T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD247; Precursor
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Pubmed References:
2
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P22087: rRNA 2'-O-methyltransferase fibrillarin; 2.1.1.-; 34 kDa nucleolar scleroderma antigen; Histone-glutamine methyltransferase
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Pubmed References:
1
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P25445: Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; CD95; Precursor
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Pubmed References:
1
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P41182: B-cell lymphoma 6 protein; BCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51
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Pubmed References:
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P42574: Caspase-3; CASP-3; 3.4.22.56; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12; Precursor
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Pubmed References:
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P42575: Caspase-2; CASP-2; 3.4.22.55; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1; Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12; Precursor
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P45985: Dual specificity mitogen-activated protein kinase kinase 4; MAP kinase kinase 4; MAPKK 4; 2.7.12.2; JNK-activating kinase 1; MAPK/ERK kinase 4; MEK 4; SAPK/ERK kinase 1; SEK1; Stress-activated protein kinase kinase 1; SAPK kinase 1; SAPKK-1; SAPKK1; c-Jun N-terminal kinase kinase 1; JNKK
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Pubmed References:
1
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P48023: Tumor necrosis factor ligand superfamily member 6; Apoptosis antigen ligand; APTL; CD95 ligand; CD95-L; Fas antigen ligand; Fas ligand; FasL; CD178; Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form; Receptor-binding FasL ectodomain; Soluble Fas ligand; sFasL; ADAM10-processed FasL form; APL; FasL intracellular domain; FasL ICD; SPPL2A-processed FasL form; SPA
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Pubmed References:
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P49411: Elongation factor Tu, mitochondrial; EF-Tu; P43; Precursor
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Pubmed References:
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P49810: Presenilin-2; PS-2; 3.4.23.-; AD3LP; AD5; E5-1; STM-2; Presenilin-2 NTF subunit; Presenilin-2 CTF subunit
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Pubmed References:
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P50591: Tumor necrosis factor ligand superfamily member 10; Apo-2 ligand; Apo-2L; TNF-related apoptosis-inducing ligand; Protein TRAIL; CD253
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P55210: Caspase-7; CASP-7; 3.4.22.60; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3; Caspase-7 subunit p20; Caspase-7 subunit p11; Precursor
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P55212: Caspase-6; CASP-6; 3.4.22.59; Apoptotic protease Mch-2; Caspase-6 subunit p18; Caspase-6 subunit p11; Precursor
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Pubmed References:
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P58107: Epiplakin; 450 kDa epidermal antigen
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Pubmed References:
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P62273: 40S ribosomal protein S29
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Pubmed References:
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P84022: Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3
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Q02750: Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; 2.7.12.2; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1
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Pubmed References:
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Q07817: Bcl-2-like protein 1; Bcl2-L-1; Apoptosis regulator Bcl-X
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Pubmed References:
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Q09472: Histone acetyltransferase p300; p300 HAT; 2.3.1.48 {ECO:0000269|PubMed:23415232, ECO:0000269|PubMed:23934153, ECO:0000269|PubMed:8945521}; E1A-associated protein p300
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Q12933: TNF receptor-associated factor 2; 6.3.2.-; E3 ubiquitin-protein ligase TRAF2; Tumor necrosis factor type 2 receptor-associated protein 3
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Q13077: TNF receptor-associated factor 1; Epstein-Barr virus-induced protein 6
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Q13114: TNF receptor-associated factor 3; 6.3.2.-; CAP-1; CD40 receptor-associated factor 1; CRAF1; CD40-binding protein; CD40BP; LMP1-associated protein 1; LAP1
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Pubmed References:
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Q13158: FAS-associated death domain protein; FAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity; Protein FADD
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Q13191: E3 ubiquitin-protein ligase CBL-B; 6.3.2.-; Casitas B-lineage lymphoma proto-oncogene b; RING finger protein 56; SH3-binding protein CBL-B; Signal transduction protein CBL-B
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Q13200: 26S proteasome non-ATPase regulatory subunit 2; 26S proteasome regulatory subunit RPN1; 26S proteasome regulatory subunit S2; 26S proteasome subunit p97; Protein 55.11; Tumor necrosis factor type 1 receptor-associated protein 2
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Pubmed References:
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Q13546: Receptor-interacting serine/threonine-protein kinase 1; 2.7.11.1; Cell death protein RIP; Receptor-interacting protein 1; RIP-1; Serine/threonine-protein kinase RIP
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Q13547: Histone deacetylase 1; HD1; 3.5.1.98
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Pubmed References:
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Q14790: Caspase-8; CASP-8; 3.4.22.61; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH; Caspase-8 subunit p18; Caspase-8 subunit p10; Precursor
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Pubmed References:
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Q15156: PML-RAR protein {ECO:0000313|EMBL:AAA60126.1}
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Pubmed References:
2
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Q15393: Splicing factor 3B subunit 3; Pre-mRNA-splicing factor SF3b 130 kDa subunit; SF3b130; STAF130; Spliceosome-associated protein 130; SAP 130
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Q16543: Hsp90 co-chaperone Cdc37; Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37; Hsp90 co-chaperone Cdc37, N-terminally processed
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Q16658: Fascin; 55 kDa actin-bundling protein; Singed-like protein; p55
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Q496A3: Spermatogenesis-associated serine-rich protein 1
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Pubmed References:
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Q53FC7: Heat shock 70kDa protein 6 (HSP70B') variant {ECO:0000313|EMBL:BAD97082.1}; Fragment
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Pubmed References:
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Q6PK50: HSP90AB1 protein {ECO:0000313|EMBL:AAH07327.1}; Fragment
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Pubmed References:
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Q8IUC6: TIR domain-containing adapter molecule 1; TICAM-1; Proline-rich, vinculin and TIR domain-containing protein B; Putative NF-kappa-B-activating protein 502H; Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta; MyD88-3; TIR domain-containing adapter protein inducing IFN-beta
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Q8IVD9: NudC domain-containing protein 3
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Pubmed References:
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Q8WXF8: DNA-binding death effector domain-containing protein 2; DED-containing protein FLAME-3; FADD-like anti-apoptotic molecule 3
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Q92851: Caspase-10; CASP-10; 3.4.22.63; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4; Caspase-10 subunit p23/17; Caspase-10 subunit p12; Precursor
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Pubmed References:
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Q96BE0: Putative uncharacterized protein {ECO:0000313|EMBL:AAH15699.1}; Fragment
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Pubmed References:
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Q96J02: E3 ubiquitin-protein ligase Itchy homolog; Itch; 6.3.2.-; Atrophin-1-interacting protein 4; AIP4; NFE2-associated polypeptide 1; NAPP1
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Q96JH8: Ras-associating and dilute domain-containing protein
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Q96P20: NACHT, LRR and PYD domains-containing protein 3; Angiotensin/vasopressin receptor AII/AVP-like; Caterpiller protein 1.1; CLR1.1; Cold autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1
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Pubmed References:
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Q99558: Mitogen-activated protein kinase kinase kinase 14; 2.7.11.25; NF-kappa-beta-inducing kinase; HsNIK; Serine/threonine-protein kinase NIK
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Q9BPW0: Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; 3.1.3.16 {ECO:0000256|RuleBase:RU004273}; Fragment
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Q9HB71: Calcyclin-binding protein; CacyBP; hCacyBP; S100A6-binding protein; Siah-interacting protein
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Pubmed References:
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Q9NT62: Ubiquitin-like-conjugating enzyme ATG3; 6.3.2.-; Autophagy-related protein 3; APG3-like; hApg3; Protein PC3-96
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Q9UER7: Death domain-associated protein 6; Daxx; hDaxx; ETS1-associated protein 1; EAP1; Fas death domain-associated protein
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Q9UH99: SUN domain-containing protein 2; Protein unc-84 homolog B; Rab5-interacting protein; Rab5IP; Sad1/unc-84 protein-like 2
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Q9UIM3: FK506-binding protein-like; WAF-1/CIP1 stabilizing protein 39; WISp39
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Pubmed References:
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Q9UNE7: E3 ubiquitin-protein ligase CHIP {ECO:0000305}; 6.3.2.- {ECO:0000269|PubMed:11557750, ECO:0000269|PubMed:15466472}; Antigen NY-CO-7 {ECO:0000303|PubMed:9610721}; CLL-associated antigen KW-8 {ECO:0000303|PubMed:12200376}; Carboxy terminus of Hsp70-interacting protein {ECO:0000303|PubMed:10330192}; STIP1 homology and U box-containing protein 1 {ECO:0000312|HGNC:HGNC:11427}
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Q9Y239: Nucleotide-binding oligomerization domain-containing protein 1; Caspase recruitment domain-containing protein 4
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Q9Y4E8: Ubiquitin carboxyl-terminal hydrolase 15; 3.4.19.12; Deubiquitinating enzyme 15; Ubiquitin thioesterase 15; Ubiquitin-specific-processing protease 15; Unph-2; Unph4
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