pathDIP is an annotated database of signaling
cascades, comprising core pathways from major curated pathways databases,
and extended pathways predicted by using physical protein interactions.
Data integration and predictions increase coverage of pathway annotations
for protein-coding genes to 86%, and provide novel annotations for 5,732
pathway orphans. PathDIP annotates 17,070 protein-coding genes with 4,678
pathways, and provides multiple query, analysis and output options.
Please cite the following paper for this database:
Sara Rahmati, Mark Abovsky, Chiara Pastrello, Igor Jurisica.
pathDIP: an annotated resource for known and predicted human gene-pathway
associations and pathway enrichment analysis.
Nucleic Acids Research 2016;