Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: P52333 and Q9Y4H2	Pubmed	SVM Score :0.0
In addition , we show that the Janus kinases , JAK 1 and JAK 3 , associate with IRS 1 and IRS 2 in T cells . ^^^
Interacting proteins: P52333 and Q9Y4H2	Pubmed	SVM Score :0.0
We demonstrate that , in addition to activation of the Jak 1 and Jak 3 kinases , IL 7 stimulation of human thymocytes results in the rapid tyrosine phosphorylation of insulin receptor substrate 1 ( IRS 1 ) and IRS 2 proteins . ^^^ We show that the Jak 1 and Jak 3 kinases are associated with both IRS 1 and IRS 2 in thymocytes . ^^^ This study suggests that IL 7R signaling diverges at the level of the IRS 1 and IRS 2 proteins , possibly with the two branches regulated by Jak 3 and Jak 1 activities , respectively . . ^^^
Interacting proteins: P52333 and Q9Y4H2	Pubmed	SVM Score :0.0
Stat 6 and JAK 3 are present in equivalent amounts in Th1s and Th2s , but IRS 2 protein levels are much lower in Th1s than in Th2s . ^^^
Interacting proteins: P52333 and Q9Y4H2	Pubmed	SVM Score :0.0
Binding of interleukin ( IL ) 4 to its transmembrane receptor results in the Jak mediated tyrosine phosphorylation of a number of protein components of the IL 4 signaling cascade , including Jak 1 , Jak 2 , Jak 3 , Tyk 2 , IL 4Ralpha , IRS 1 , IRS 2 , and Stat 6 in appropriate cell types . ^^^
Interacting proteins: P52333 and Q9Y4H2	Pubmed	SVM Score :0.0
Treatment with H 7 did not affect IL 4R mediated immediate signaling events such as tyrosine phosphorylation of Jak 1 , Jak 3 , insulin receptor substrate ( IRS ) 1 and IRS 2 , or tyrosine phosphorylation and DNA binding of Stat 6 . ^^^
Interacting proteins: P52333 and Q9Y4H2	Pubmed	SVM Score :0.0
NA
Interacting proteins: P52333 and Q9Y4H2	Pubmed	SVM Score :0.0
NA
Interacting proteins: P52333 and Q9Y4H2	Pubmed	SVM Score :0.0
NA
Interacting proteins: P52333 and Q9Y4H2	Pubmed	SVM Score :0.0
NA
Interacting proteins: P52333 and Q9Y4H2	Pubmed	SVM Score :0.0
NA