Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: P29597 and Q9Y4H2 Pubmed SVM Score :0.52079045
We also provide evidence for an interaction of IRS 2 with Tyk 2 , suggesting that Tyk 2 is the kinase that phosphorylates this protein during IFN alpha stimulation . 0.52079045^^^
Interacting proteins: P29597 and Q9Y4H2 Pubmed SVM Score :0.0
S , conferred the ability to grow continuously in response to IL 13 ; to respond to IL 13 with tyrosine phosphorylation of JAK 1 , Tyk 2 , IL 4Ralpha , IRS 2 , and STAT 6 ; and to respond to IL 4 with tyrosine phosphorylation of Tyk 2 in addition to those induced in parental cell lines . ^^^
Interacting proteins: P29597 and Q9Y4H2 Pubmed SVM Score :0.0
Binding of interleukin ( IL ) 4 to its transmembrane receptor results in the Jak mediated tyrosine phosphorylation of a number of protein components of the IL 4 signaling cascade , including Jak 1 , Jak 2 , Jak 3 , Tyk 2 , IL 4Ralpha , IRS 1 , IRS 2 , and Stat 6 in appropriate cell types . ^^^
Interacting proteins: P29597 and Q9Y4H2 Pubmed SVM Score :0.0
In normal cells , we detected the activation of the classic IRS 2 or JAK1 / STAT6 pathways , the phosphorylation of JAK 2 , while Tyk 2 was constitutively phosphorylated and not modified by both cytokines . ^^^
Interacting proteins: P29597 and Q9Y4H2 Pubmed SVM Score :0.0
Jak 1 , Tyk 2 and IRS 2 signals were reduced after IL 13 stimulation in Q 551 individuals . ^^^ SHP 1 seems to be predominately activated by IL 4 and to influence the PI 3 kinase , in contrast , SHP 2 seems to be predominately activated by IL 13 and to influence Jak 1 , Tyk 2 and IRS 2 . ^^^
Interacting proteins: P29597 and Q9Y4H2 Pubmed SVM Score :0.0
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Interacting proteins: P29597 and Q9Y4H2 Pubmed SVM Score :0.0
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Interacting proteins: P29597 and Q9Y4H2 Pubmed SVM Score :0.0
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Interacting proteins: P29597 and Q9Y4H2 Pubmed SVM Score :0.0
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Interacting proteins: P29597 and Q9Y4H2 Pubmed SVM Score :0.0
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