| Interacting proteins: Q9Y4H2 and P04629 |
Pubmed |
SVM Score :0.0 |
| IRS 1 and IRS 2 are recruited by TrkA receptor and oncogenic TRK T 1 . ^^^ Here , we show that IRS 1 and IRS 2 are phosphorylated on tyrosine in presence of both TRK T 1 and the activated TrkA receptor . ^^^ Furthermore , we found that TRK T 1 is able to activate c fos serum responsive element in cooperation with IRS 1 and IRS 2 . ^^^ On the whole , our results suggest that IRS 1 and IRS 2 could be substrates of TRK T 1 and TrkA , and hence could participate in their signal generation . . ^^^ |
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| Interacting proteins: Q9Y4H2 and P04629 |
Pubmed |
SVM Score :0.0 |
| The signaling pathway that controls the level of TrkA and p 75 ( NTR ) downstream of the IGF 1 R requires IRS 2 , PIP3 / Akt , and is under the control of PTEN and p 44 , the short isoform of p 53 . ^^^ |
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| Interacting proteins: Q9Y4H2 and P04629 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q9Y4H2 and P04629 |
Pubmed |
SVM Score :0.0 |
| NA |
|