| Interacting proteins: Q9BX66 and O15357 |
Pubmed |
SVM Score :0.0 |
| Using yeast two hybrid , GST pulldown , and coimmunoprecipitation studies , we isolated the CAP cDNA as a specific partner of SHIP 2 proline rich domain and showed by GST pulldown experiments that the interaction took place with the SH3C of CAP . ^^^ We also showed that SHIP 2 was able to coimmunoprecipitate with endogenous c Cbl protein in the absence of CAP and with the insulin receptor in CHO IR cell extracts . ^^^ |
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| Interacting proteins: Q9BX66 and O15357 |
Pubmed |
SVM Score :0.0 |
| Our two hybrid study showed that SHIP 2 interacts with c Cbl associated protein ( CAP ) and c Cbl , implicated in the insulin signaling . ^^^ As some proteins implicated in insulin signaling , like insulin receptor , CAP , c Cbl or TC 10 , were reported to localize in lipid rafts , we addressed the same question for SHIP 2 . ^^^ |
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| Interacting proteins: Q9BX66 and O15357 |
Pubmed |
SVM Score :0.0 |
| NA |
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