| Interacting proteins: Q99717 and Q04771 |
Pubmed |
SVM Score :0.0 |
| Biochemical analysis revealed that constitutively active ALK 2 associated with and phosphorylated Smad 1 on the COOH terminal SSXS motif , and also regulated Smad 5 and Smad 8 phosphorylation . ^^^ |
|
| Interacting proteins: Q99717 and Q04771 |
Pubmed |
SVM Score :0.0 |
| These findings indicate that in the process of differentiation to osteoblasts , BMP 6 binds to ALK 2 as well as other type 1 receptors , and transduces signals mainly through Smad 5 and possibly through Smad1 . . ^^^ |
|
| Interacting proteins: Q99717 and Q04771 |
Pubmed |
SVM Score :0.0 |
| Expression of constitutively active BMP receptor ALK 2 activating Smad 1 and Smad 5 resulted in a strong increase in the SBE ( 4x ) luc reporter response . ^^^ |
|
| Interacting proteins: Q99717 and Q04771 |
Pubmed |
SVM Score :0.0 |
| GREM 1 ( CKTSF1B1 ) inhibits BMP signaling through BMPR1A ( ALK 3 ) , BMPR1B ( ALK 6 ) or ACVR 1 ( ALK 2 ) to SMAD 1 , SMAD 5 or SMAD 8 . ^^^ |
|
| Interacting proteins: Q99717 and Q04771 |
Pubmed |
SVM Score :0.0 |
| MIS induces expression of Alk 2 , Alk 3 and Smad 8 , but downregulates Smad 5 in the urogenital ridge . ^^^ |
|
| Interacting proteins: Q99717 and Q04771 |
Pubmed |
SVM Score :0.0 |
| BMP 6 increased in vivo the bone expression of Acvr 1 , Bmpr1b , Smad 5 , alkaline phosphatase , and collagen type 1 and decreased expression of Bmp 3 and BMP antagonists , chordin and cerberus . ^^^ |
|
| Interacting proteins: Q99717 and Q04771 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q99717 and Q04771 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q99717 and Q04771 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q99717 and Q04771 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q99717 and Q04771 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q99717 and Q04771 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q99717 and Q04771 |
Pubmed |
SVM Score :0.0 |
| NA |
|