Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: P98170 and P31751 Pubmed SVM Score :0.0
Here , we demonstrate that Akt , including AKT 1 and AKT 2 , interacts with and phosphorylates 10 linked inhibitor of apoptosis protein ( XIAP ) at residue serine 87 in vitro and in vivo . ^^^
Interacting proteins: P98170 and P31751 Pubmed SVM Score :0.0
Expression of a constitutively active Akt 2 prevented CDDP mediated down regulation of Xiap and apoptosis in A2780s cells . ^^^ Akt 2 mediated chemoresistance could not be reversed by Xiap down regulation . ^^^ These results suggest that whereas Xiap , Akt 2 , and p 53 are important mediators of chemoresistance in ovarian cancer cells , Akt 2 may be an important regulator of both Xiap and p 53 contents after CDDP challenge . ^^^
Interacting proteins: P98170 and P31751 Pubmed SVM Score :0.0
Activation of XIAP expression by HGF was inhibited by siRNA targeting Akt 1 and Akt 2 . ^^^