| Here we show that , in contrast to Akt 1 and Akt 2 , which bind to all members of the TCL 1 family , Akt 3 specifically interacts with TCL 1 but not with MTCP 1 or TCL1b . ^^^ Moreover , we show that , in TCL 1 overexpressing SUPT 11 T cell leukemia and P3HR 1 Burkitt ' s lymphoma cell lines , TCL 1 interacts with endogenous Akt 1 , Akt 2 , and Akt 3 . ^^^ |