| Interacting proteins: P14735 and P10275 |
Pubmed |
SVM Score :0.83118807 |
| The interactions of AR and GR with IDE may have important implications for both insulin and steroid mediated signaling . . 0.83118807^^^ |
|
| Interacting proteins: P14735 and P10275 |
Pubmed |
SVM Score :0.0 |
| Further , a western blot analysis revealed that a cytosolic protein of 110 kD , in both human colon and ileum , reacted with the monoclonal antibody to insulin degrading enzyme . ^^^ |
|
| Interacting proteins: P14735 and P10275 |
Pubmed |
SVM Score :0.0 |
| In addition to the known substrates , insulin and transforming growth factor alpha IDE binds also with high affinity ( apparent Kd 60 nM ) to ANP . ^^^ |
|
| Interacting proteins: P14735 and P10275 |
Pubmed |
SVM Score :0.0 |
| With increasing amounts of IDE , the radioactivity of 135 kd band ( insulin receptor alpha subunit ) decreased , whereas that of 110 kd band ( IDE ) appeared then gradually increased , suggesting that IDE could bind to receptor bound insulin . ^^^ |
|
| Interacting proteins: P14735 and P10275 |
Pubmed |
SVM Score :0.0 |
| Third , kinetic studies of insulin degradation by RIA active chromatographic fractions revealed an apparent Kd of 90 nM which is very similar to the reported affinity of insulin for IDE ( Kd = 100 nM ) . ^^^ |
|
| Interacting proteins: P14735 and P10275 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14735 and P10275 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14735 and P10275 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14735 and P10275 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P14735 and P10275 |
Pubmed |
SVM Score :0.0 |
| NA |
|