| We now show here in Chinese hamster ovary cells stably transfected with rat GH receptor cDNA that human ( h ) GH induces the formation of a large multiprotein signaling complex centered around another FAK associated protein , p 130 ( Cas ) and the adaptor protein CrkII . hGH stimulates the tyrosine phosphorylation of both p 130 ( Cas ) and CrkII , their association , and the association of multiple other tyrosine phosphorylated proteins to the complex . ^^^ |