Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.72185865
In this cell system , STAT 5 directly interacts with the GHR in a GH dependent manner . 0.72185865^^^ Therefore , the GH dependent interaction of a particular STAT 5 with tyrosine phosphorylated GHR may play an important role in GH mediated signal transduction . . 0.56626721^^^ Additionally , GH induced tyrosine phosphorylation of STAT 5 and the interaction of STAT 5 with GHR can be observed in mouse 3T3 F442A cells which express endogenous mouse GHR . 0.55298207^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Activation of Stat 5 by GH was , however , abolished in cells expressing the GH receptor lacking intracellular tyrosines . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Western blotting indicates that GH also activates STAT 5 in human embryonic kidney cells ( 293 ) , which stably express the rabbit GH receptor . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Furthermore , in COS 7 cells transiently transfected with STAT 5 and GH receptor cDNAs , it was found that expression of STAT 5 was necessary for GH induction of these two DNA binding complexes . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
It has been previously demonstrated that growth hormone ( GH ) stimulated tyrosine phosphorylation of Jak 2 and Stat5a and Stat5b occurs in FDP C 1 cells expressing either the entire GH receptor or truncations of the cytoplasmic domain expressing only the membrane proximal 80 amino acids . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
The role of GH receptor tyrosine phosphorylation in Stat 5 activation . ^^^ Similarly , these GH receptors were found to be able to mediate activation of Stat 5 DNA binding activity , whereas the GH receptor mutant lacking all intracellular tyrosines was not . ^^^ Synthetic tyrosine phosphorylated peptides corresponding to the GH receptor sequence around the three tyrosines inhibited Stat 5 DNA binding activity while their non phosphorylated counterparts were ineffective . ^^^ Tyrosine phosphorylated GST GH receptor fusion proteins specifically bound to Stat 5 in extracts from COS 7 cells transfected with Stat 5 cDNA . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
In this paper , we demonstrate ( in COS cells expressing rat GH receptor ( rGHR ) and either Stat5A or Stat5B , 3T3 F442A fibroblasts , and CHO cells expressing rGHR ) that GH induces tyrosyl phosphorylation of both Stat5A and Stat5B . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
BRL cells expressing the GH receptor were transiently transfected with expression plasmids containing either the hGH or the bGH gene and the response of the cell was measured by CAT reporter plasmids requiring either STATs 1 and 3 or STAT 5 for their response . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Continuous exposure to GH of BRL 4 cells , a rat hepatoma cell line stably transfected with rat GH receptor , induces a rapid but transient activation of Jak 2 and Stat 5 . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
GH treatment of Chinese hamster ovary cells stably transfected with the GH receptor ( CHOA cells ) led to rapid and transient activation of both STAT5a and ERK 1 and ERK 2 . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
All four SOCS proteins were able to bind to a tyrosine phosphorylated glutathione S transferase GH receptor fusion protein , and SOCS 3 required the same 46 C terminal amino acids for GH receptor binding as it did for inhibition of GH mediated transcription and STAT 5 activation . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
The finding of endotoxin inhibition of in vivo STAT 5 tyrosine phosphorylation in response to a supramaximal dose of GH in the absence of a change in GH receptor abundance or total GH stimulated JAK 2 tyrosine phosphorylation provides the first demonstration of acquired postreceptor GH resistance . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
We therefore tested the C2C12 myogenic cell line for its response to GH and demonstrate that C2C12 skeletal muscle cells rapidly respond to physiological levels of GH with increased tyrosine phosphorylation of the GH receptor , Janus kinase 2 , signal transducer and activator of transcription 5a and 5b , insulin receptor substrate 1 , and activation of MAPKs / ERKs and protein kinase B / Akt . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
In HepG 2 cells transiently cotransfected with either the long form of the rat PRL receptor or rat GH receptor , signal transducer and activator of transcription 5a and a 5 responsive luciferase expression vector containing the Na ( + ) / taurocholate cotransporting polypeptide promoter , mouse placental lactogen 1 , like ovine PRL , activated 5a via the long form of the rat PRL receptor ; whereas rat GH activated 5a via rat GH receptor , leading to transactivation of the Na ( + ) / taurocholate cotransporting polypeptide promoter . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
The effects of continuous high GH levels on GH signal transduction through the GH receptor ( GHR ) / Janus kinase 2 ( JAK 2 ) / signal transducer and activator of transcription 5 ( STAT 5 ) pathway as well as the desensitization of this pathway by suppressors of cytokine signaling ( SOCS ) were studied in transgenic mice overexpressing GHRH . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
GH stimulated tyrosine phosphorylation of the GH receptor , signal transducer and activator of transcription 3 ( Stat 3 ) , and Stat 5 . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
The exogenous expression of the GH receptor in one family of LS fibroblasts ( H 1 ) but not the other ( M ) restores signaling to a STAT 5 reporter element . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
We have reported that TNF alpha suppresses hepatic GH receptor ( GHR ) gene expression , whereas the cytokine inducible SH 2 containing protein 1 ( Cis ) / suppressors of cytokine signaling ( Socs ) genes are upregulated by TNF alpha and IL 6 and inhibit GH activation of STAT 5 . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
To investigate the mechanism involved , we studied the effects of estrogen on GH signaling through Janus kinase ( JAK ) 2 and the signal transducers and activators of transcription ( STATs ) in HEK 293 cells stably expressing the GH receptor ( 293GHR ) , HuH 7 ( hepatoma ) and T 47D ( breast cancer ) cells . 293GHR cells were transiently transfected with an estrogen receptor alpha expression plasmid and luciferase reporters with binding elements for STAT 3 and STAT 5 or the beta casein promoter . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
The expression of MUP 2 is known to be stimulated by growth hormone ( GH ) , through the GH receptor ( GHR ) , Janus kinase 2 ( JAK 2 ) and signal transducer and activator of transcription 5 ( STAT 5 ) signal transduction pathway . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
SOCS 2 binds to the GH receptor and inhibits GH signaling , including attenuation of STAT 5 activation . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Growth hormone ( GH ) insensitivity syndrome due to a GH receptor truncated after Box 1 , resulting in isolated failure of STAT 5 signal transduction . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
This could account for the inhibition of STAT 5 activation , because CIS competes with STAT 5 for GH receptor docking sites . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
In liver , these responses were associated with increased abundance of the GH receptor protein ( GHR ; P < 0 . 05 ) , whereas the abundance of intracellular mediators of GH actions ( JAK 2 , STAT 5 , or STAT 3 ) remained unaffected . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
GH activated Janus associated kinase 2 ( JAK 2 ) signal transducers and activators of transcription 5 ( STAT 5 ) signaling was impaired in CRF rats , despite normal GH receptor ( GHR ) , JAK 2 , and STAT 5 protein levels . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Total GH receptor ( GHR ) , JAK 2 , and STAT 5 signaling proteins and the time course of STAT 5 activation were also measured in liver after recombinant human GH administration by immunoblot and electrophoretic mobility shift analysis . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
At the tissue level , the action of GH is mediated by the GH receptor ( GHR ) and the receptor activated intracellular signaling pathway involving Janus kinase 2 ( JAK 2 ) and signal transducer and activator of transcription 5 ( STAT 5 ) . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
In order to establish whether the prolactin activated transcription factor Stat 5 ( mammary gland factor ) is also activated by growth hormone , nuclear extracts were prepared from COS 7 cells transiently expressing transfected Stat 5 and growth hormone receptor cDNA . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Differential activation of Stat 3 and Stat 5 by distinct regions of the growth hormone receptor . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Identification of growth hormone receptor ( GHR ) tyrosine residues required for GHR phosphorylation and JAK 2 and STAT 5 activation . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Activation of STAT 5 was also observed after growth hormone treatment of cells transfected with cDNA expression plasmids for several different truncated growth hormone receptor mutants , although this activation was less efficient than with the wild type receptor . ^^^ Point mutation of individual tyrosines in the growth hormone receptor intracellular domain to phenylalanines had no significant effect on signal transduction via STAT 5 . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
The aim of this study was to investigate the interaction of Stat 5 with key effector proteins Erk 2 and Shc after activation by growth hormone ( GH ) , using Chinese Hamster Ovary ( CHO ) cells stably expressing the wild type rabbit growth hormone receptor ( GHR ) . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
A novel C terminal growth hormone receptor ( GHR ) mutation results in impaired GHR STAT 5 but normal STAT 3 signaling . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Growth hormone induced JAK 2 , growth hormone receptor ( GHR ) , and STAT 5 tyrosine phosphorylation was significantly depressed in CRF as was nuclear translocation of phosphorylated STAT 5 . ^^^ Growth hormone receptor , JAK 2 , STAT5a , and STAT5b protein levels were unaltered in CRF . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
GH dependent tyrosyl phosphorylation of Stat 5 , but not Stats 1 or 3 , was reduced in CHO cells expressing GHR 1 454 . ^^^ These findings suggest that : 1 ) JAK 2 is required for GH dependent phosphorylation of Stats 1 , 3 , and 5 ; 2 ) tyrosines 333 and / or 338 are required for maximal tyrosyl phosphorylation of Stats 1 , 3 , and 5 ; 3 ) Stat 5 binds to a phosphorylated tyrosine ( s ) within amino acids 454 638 in addition to tyrosines 333 and / or 338 ; 4 ) GH stimulates tyrosyl phosphorylation of JAK 1 in addition to JAK 2 with JAK 2 having a much greater response ; 5 ) some Stat 3 and Stat 5 ( and possibly Stat 1 ) may bind to nonphosphorylated amino acids in GHR or to phosphorylated tyrosines in proteins that bind to GHR ( e . g . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Mutant GH was less potent than wild type GH not only in phosphorylation of tyrosine residues in GHR , janus kinase 2 ( JAK 2 ) , and signal transducers and activators of transcription 5 ( STAT 5 ) in IM 9 cells , but also in metabolic responses of BaF / GM cells , a stable clone transfected with cDNA of the chimera of the extracellular domain of human GHR , the transmembrane and the cytoplasmic domain of the human thrombopoietin receptor . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Mutant human receptor protein was expressed at a lower level than wild type receptor and its activity was reduced : GH dependent signal transducer and activator of transcription 5 ( Stat 5 ) mediated transactivation of a reporter gene was lower in 293 cells transfected with mutant GHR cDNA than in transfected cells expressing a comparable level of wild type GHR . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Moreover , in GH induced tyrosine phosphorylation of signal transducer and activator of transcription 5 ( STAT 5 ) , GHR 277 exerted a dominant negative effect when GHR 277 and GHR fl were cotransfected . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
By using both transient and stable expression systems , we determined that cysteine 241 ( an unpaired extracellular cysteine ) was critical for GH induced GHR disulfide linkage ; however , GH induced GHR dimerization , GHR JAK 2 interaction , and GHR , JAK 2 , and STAT 5 tyrosine phosphorylation still proceeded when this cysteine residue was mutated . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Moreover , STAT 5 mediated transcriptional activation of GHR C422F expressing cells was comparable to that of GHR wt expressing cells . ^^^ These findings indicated that the C422F mutation of GHR affected neither GH induced tyrosine phosphorylation nor the transcriptional activation of STAT 5 . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
However , GH was unable to cause transactivation of reporter gene constructs harboring Stat 5 binding sites ( the GHREII from the rat spi 2 . 1 gene promoter , and the LHRE from the rat beta casein gene promoter ) , except in cells transiently transfected with either Stat 5 cDNAs or the rat GHR cDNA . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Whereas bone length was reduced in Stat5ab ( / ) mice , there was no reduction in trabecular bone remodeling or growth plate width as observed in GHR ( / ) mice , indicating that the effects of GH in bone may not involve Stat 5 activation . . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Although at high concentrations binding of pGH to the canine PRLR can occur ( albeit with a low pKa ) , the similar dose dependent effect of oPRL on Stat5a phosphorylation indicated that pGH signaled through the GHR . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Recovery of GH induced STAT 5 phosphorylation correlated with the time dependent recovery of GHR levels during incubation in the absence of GH . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
The signal transducer and activator of transcription 5 ( STAT 5 ) mediated transcriptional activation in mutant GHR ( GHR T51I ) expressing cells was significantly reduced as compared with wild type GHR ( GHR wt ) expressing cells . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Upon GH stimulation of the GHR positive CMT U 335 canine mammary tumor cell line , the transcription factors STAT5A and STAT5B become phosphorylated on their tyrosine residues , which is likely to reflect the significance of mammary GH in vivo . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
In C2C12 ( GHR ) cells , we observed an increased activation of the Janus kinase 2 ( Jak 2 ) , signal transducers and activator of transcription 5 ( Stat 5 ) , mitogen activated protein kinase ( MAPK ) and protein kinase B ( Akt ) upon acute GH stimulation . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
The effect of heterodimerization was studied by comparing activation of Janus kinase 2 , signal transducer and activator of transcription ( STAT ) 1 , STAT 3 , STAT 5 , and MAPK in Chinese hamster ovary cells stably transfected with chimeric genes encoding receptors consisting of cytosolic and transmembrane parts of oGHR and oPRLR , extracellular domains of human granulocyte and macrophage colony stimulating factor ( hGM CSF ) receptor alpha or beta , and cells transfected with the two forms ( alpha or beta ) of PRLR and GHR . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Since GH regulates cellular cytoskeleton with potential implications in GH signaling , we investigated the effects of actin cytoskeleton disruption on the kinetics of GH activated GHR / Janus kinase 2 ( JAK 2 ) / signal transducer and activator of transcription 5 ( STAT 5 ) signaling pathway . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Correspondingly , GH induced tyrosine phosphorylated GHR , JAK 2 , and ERK1 / 2 were highly represented in the CM fraction , whereas tyrosine phosphorylated STAT 5 was enriched in the non membranous fraction of the post nuclear supernatant . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
In the cell cultures , STAT 5 ( signal transducer and activator of transcription 5 ) phosphorylation was measured by Western blot analysis as an index of GHR signalling ; cell proliferation was evaluated by [ H 3 ] thymidine incorporation and glycoprotein hormone production analysed by radioimmunoassay ( RIA ) . ^^^ RESULTS : All adenomas investigated expressed the GHR , but there was no detection of STAT 5 phosphorylation . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Furthermore , GH induced rapid , time and dose dependent signaling events in LNCaP cells , including phosphorylation of JAK 2 tyrosine kinase , of GHR itself and of STAT5A ( JAK 2 STAT5A pathway ) , of p42 / p44 MAPK and of Akt / PKB . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
MGF mRNA in skeletal muscle was increased in bGH mice whereas it was decreased in GHR / mice compared with control animals . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
We hypothesized that reduced IGF 1 expression in obstructive cholestasis would be associated with downregulation of the GHR and impaired phosphorylation of signal transducers and activators of transcription ( STAT 5 ) . ^^^ GHR , STAT 5 , Sp 3 , and IGF 1 expression and / or DNA binding were assessed using immunoblots , electrophoretic mobility shift assays , and / or real time RT PCR . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
HepG 2 cells were transiently transfected with expression vectors containing Oatp1b2 or OATP1B3 promoter fragments , cDNAs for Stat5a , and the receptors for PRL ( PRLR ( L ) ) or GH ( GHR ) , and treated with PRL or GH . ^^^ PRL and GH induction of Oatp1b2 and OATP1B3 promoter activity required cotransfection of Stat5a and PRLR ( L ) or GHR . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
TNFalpha down regulated GHR abundance and prevented GH induced tyrosine phosphorylation of STAT 5 in rat hepatocytes in culture . ^^^ TNFalpha neutralization up regulated liver GHR abundance and restored GH activation of STAT 5 and serum insulin like growth factor 1 levels in colitic mice ; this preceded improvements in weight gain and disease activity . ^^^ CONCLUSIONS : GH resistance in experimental colitis is caused by down regulation of GHR expression , thereby reducing GH dependent STAT 5 activation . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
Western blot analysis showed GH induced phosphorylation of Jak 2 and Stat 5 for both GHR 1 656 and GHRwt , although reduced Stat 5 activity was detected with GHR 1 656 , consistent with lower levels of expression of GHR 1 656 than GHRwt at the cell surface . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
To that end , we compared : ( a ) the expression of GHR and PRLR mRNAs in 3T3 L 1 preadipocytes during the course of adipocyte differentiation ; ( b ) the induction of STAT 5 activity by GH and PRL during adipogenesis ; and ( c ) the acute effects of GH and PRL on the suppressors of cytokine signaling ( SOCS 1 3 and cytokine inducible SH 2 domain containing protein CIS ) and IGF 1 . ^^^ Our findings reveal disparities in the expression of PRLR and GHR during adipocyte development and differential effects of the hormones on STAT 5 , the SOCS proteins , CIS , and IGF 1 . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
To study GHR dimerization or GH induced conformational change of predimerized GHRs and STAT 5 activation kinetics in intact cells , fluorescence resonance energy transfer ( FRET ) and live cell imaging methods were employed . ^^^ FRET measurements at the membrane of HEK 293T cells co expressing GHRs tagged at the C terminus with cyan ( C ) and yellow ( Y ) fluorescent proteins ( FPs ) revealed transient GHR dimerization lasting 2 3 min , with a maximum at 3 min after GH stimulation , which was sufficient to induce STAT 5 activation . ^^^ YFP tagged STAT 5 recruitment to the membrane , binding to GHR CFP , and phosphorylation , occurred within minutes of GH stimulation . ^^^ Although GHR dimerization and STAT 5 activation have been reported previously , this is the first spatially resolved demonstration of GHR signaling kinetics in intact cells . . ^^^
Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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Interacting proteins: P10912 and P42229	Pubmed	SVM Score :0.0
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