| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| Stat 5 is a physiological substrate of the insulin receptor . ^^^ |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| We therefore tested the C2C12 myogenic cell line for its response to GH and demonstrate that C2C12 skeletal muscle cells rapidly respond to physiological levels of GH with increased tyrosine phosphorylation of the GH receptor , Janus kinase 2 , signal transducer and activator of transcription 5a and 5b , insulin receptor substrate 1 , and activation of MAPKs / ERKs and protein kinase B / Akt . ^^^ |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| Based on the characteristics of the inhibition of tyrosine kinase shown by fluoride it might be proposed that its action is exerted by the formation of multi ionic MgF complexes analogous to Pi , which bind to the insulin receptor kinase . . ^^^ |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| Growth hormone stimulates tyrosine phosphorylation of JAK 2 and STAT 5 , but not insulin receptor substrate 1 or SHC proteins in liver and skeletal muscle of normal rats in vivo . ^^^ |
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| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| Although IL 2 induced phosphorylation of IL 2R beta , JAK 1 , and STAT 5 all required the presence of JAK 3 , IL 4 mediated phosphorylation of JAK 1 , STAT 6 , and insulin receptor substrates 1 and 2 did not . ^^^ |
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| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| The injection of peroxovanadate also enhanced the tyrosine phosphorylation of many of the proteins known to function downstream of these receptors , including SHC , signal transducer and activator of transcription ( Stat ) 1alpha , beta , Stat 3 , Stat 5 , phospholipase C gamma , insulin receptor substrate 1 , GTPase activating protein , beta catenin , gamma catenin , p120cas , SHP 1 , and SHP 2 . ^^^ |
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| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| TNF downregulated insulin induced insulin receptor kinase activity and insulin induced activation of the transcription factor STAT 5 . ^^^ |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| A cellular reporter assay to monitor insulin receptor kinase activity based on STAT 5 dependent luciferase gene expression . ^^^ A highly sensitive method for determination of insulin receptor ( IR ) kinase activity in whole cells , which is based on a STAT 5 ( signal transducer and activator of transcription 5 ) dependent reporter gene assay , has been developed . ^^^ |
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| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| Stimulation of pancreatic beta cell proliferation by growth hormone is glucose dependent : signal transduction via janus kinase 2 ( JAK 2 ) / signal transducer and activator of transcription 5 ( STAT 5 ) with no crosstalk to insulin receptor substrate mediated mitogenic signalling . ^^^ |
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| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| Activation of STAT 5 is typically mediated by JAK 2 , but more recent data indicate a direct activation by the insulin receptor kinase . ^^^ |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| Signaling by OSMRbeta containing receptors was characterized by highest activation of STAT 5 and ERK , recruitment of the insulin receptor substrate and Jun N terminal kinase pathways , and induction of a characteristic pattern of acute phase proteins . ^^^ |
|
| Interacting proteins: P42229 and P06213 |
Pubmed |
SVM Score :0.0 |
| Insulin stimulates signal transducer and activator of transcription 5 ( Stat 5 ) activation in insulin receptor ( IR ) overexpressing cell lines and in insulin target tissues of mice . ^^^ |
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