| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| We had earlier reported that the human serum alpha 2 HS glycoprotein ( 1 ) is a physiological and specific inhibitor of the human insulin receptor tyrosine kinase ( IR TK ) . ^^^ |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| Serum alpha 2 HS glycoprotein is an inhibitor of the human insulin receptor at the tyrosine kinase level . ^^^ |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| Recombinant human alpha 2 HS glycoprotein inhibits insulin stimulated mitogenic pathway without affecting metabolic signalling in Chinese hamster ovary cells overexpressing the human insulin receptor . ^^^ |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| Human recombinant alpha 2 HS glycoprotein is produced in insect cells as a full length inhibitor of the insulin receptor tyrosine kinase . ^^^ |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| At the molecular level , a number of negative modulator and feedback systems somehow interacting with the beta subunit ( catecholamine , phorbolester , or tumor necrosis factor alpha induced serine / threonine phosphorylation , carboxy terminal trimming by a thiol dependent protease , association of inhibitory / regulatory proteins such as RAD , PC 1 , PED , alpha 2 HS glycoprotein ) have been identified as candidate mechanisms for the impairment of insulin receptor function by elevations in the activity and / or amount of the corresponding modification enzymes / inhibitors . ^^^ |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| Genetic mapping and functional studies of a natural inhibitor of the insulin receptor tyrosine kinase : the mouse ortholog of human alpha 2 HS glycoprotein . ^^^ |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| Fetuin A has been identified as a major protein during fetal life and is also involved in important functions such as inhibition of the insulin receptor tyrosine kinase activity , protease inhibitory activities and development associated regulation of calcium metabolism and osteogenesis . ^^^ |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| A2HS is involved in important functions such as inhibition of the tyrosine kinase activity of the insulin receptor , regulation of calcium metabolism and osteogenesis as well as protease inhibitory activity . ^^^ |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| AHSG and pp 63 are involved in important functions such as inhibition of insulin receptor tyrosine kinase activity , inhibition of protease activities , and regulation of calcium metabolism and osteogenesis . ^^^ |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| OBJECTIVE : Human fetuin / alpha ( 2 ) HS glycoprotein ( AHSG ) is a 49 kDa serum and tissue protein which is a natural inhibitor of insulin receptor signaling . ^^^ |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| Alpha ( 2 ) Heremans Schmid glycoprotein ( AHSG ) is a plasma protein inhibiting the activity of the insulin receptor tyrosine kinase . ^^^ |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| AHSG is a natural inhibitor of the insulin receptor tyrosine kinase , and AHSG null mice exhibit significantly enhanced insulin sensitivity . ^^^ |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P02765 and P06213 |
Pubmed |
SVM Score :0.0 |
| NA |
|