| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.7097246 |
| Although lacking classical receptor binding determinants , INS 6 binds to and activates the human insulin receptor . 0.7097246^^^ |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| Both INS and IGF 1 activated signal transduction in maturing human erythropoietic cells as determined by phosphorylation of the insulin receptor substrate 2 ( IRS 2 ) protein . ^^^ |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| The injection of tyrphostin B 46 , a potent inhibitor of insulin receptor ( IR ) associated tyrosine kinase activity , led to a drastic reduction in MET stimulated GS activity in the presence of INS . ^^^ |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| Myocardial glut 1 , glut 4 , insulin receptor ( Ins R ) and insulin like growth factor 1 receptor ( IGF 1 R ) protein levels were unaffected by 36 weeks of chronic exercise . ^^^ |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| To further distinguish between the contributions of these two signaling pathways to the inhibition of secretion , we studied effects of insulin , because the insulin receptor links to PI 3 kinase but not to pathways postulated to generate Ins ( 3 , 4 , 5 , 6 ) P ( 4 ) . ^^^ |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| By V 8 endoproteinase digestion and circular dichroism analysis , as well as insulin receptor binding assay , we deduce that Ins ( B ) / IGF 1 ( A ) , isomer 2 of mini IGF 1 , and isomer 2 of Ins ( A ) / IGF 1 ( B ) adopt native IGF 1 / insulin like three dimensional structure with native disulfides , while isomer 1 of mini IGF 1 and isomer 1 of Ins ( A ) / IGF 1 ( B ) adopt the swap IGF 1 like three dimensional structure with swap disulfides . . ^^^ |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| Focusing our studies in day 2 ( hyperglycaemia / hyperinsulinaemia ) and day 5 ( normoglycaemia / hyperinsulinaemia ) we found , particularly in day 5 , that the early steps of the insulin signalling cascade in skeletal muscle of glucose infused rats were not more activated when compared to control animals as assessed by a comparable phosphorylation of the insulin receptor , IRS 1 and PKB and by an unaltered IRS 1 associated Ptd ( Ins ) 3 ' kinase activity . ^^^ |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| The body weight , water and food intake , fasting blood glucose ( FBG ) , glucose tolerance , plasma lipids , serum insulin , and insulin receptor ( Ins R ) were determined . ^^^ |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| The insulin gene ( INS ) , insulin receptor gene ( INSR ) and insulin receptor substrate 1 gene ( IRS 1 ) have been proposed as candidate genes . ^^^ |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| Twenty Black families in which at least two siblings had non insulin dependent diabetes mellitus ( NIDDM ) were typed for restriction fragment length polymorphisms at the insulin ( INS ) , insulin receptor ( INSR ) , and HLA DR beta loci . ^^^ We conclude that the INS and INSR loci can be ruled out as major susceptibility loci for NIDDM in most Black families segregating this disorder , but we recognize that defects at either of these loci may cause or contribute to NIDDM in some patients . ^^^ In addition , it is possible that variation at the INS and / or INSR loci may contribute to NIDDM susceptibility by modifying susceptibility due primarily to another major gene ( s ) or as part of an overall polygenic component to NIDDM . . ^^^ |
|
| Interacting proteins: P06213 and P01308 |
Pubmed |
SVM Score :0.0 |
| All animals were fed for 8 weeks , fasting blood glucose ( FBG ) , blood glucose ( BG ) levels 1 and 2 hrs after glucose loading were determined routinely , serum fasting insulin ( Ins ) was determined with radioimmunoassay ( RIA ) and tyrosine phosphorylation level of InsR and IRS 1 in fatty and muscular tissues was measured by immunoprecipitation and Western blot . ^^^ |
|