Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: Q16270 and P01344	Pubmed	SVM Score :0.0
IGFBPs 1 6 bind IGF 1 and IGF 2 with high affinity whereas IGFBP 7 , a newly identified IGFBP , binds IGFs with lower affinity and constitutes a low affinity member of the IGFBP family . ^^^
Interacting proteins: Q16270 and P01344	Pubmed	SVM Score :0.0
Binding of insulin to IGFBP 3 and its N and C terminal fragments and of IGF 1 and IGF 2 to the structurally related proteins mac 25 and connective tissue growth factor was also investigated . ^^^ Weak insulin binding to full length IGFBP 3 could be demonstrated in a few experiments , but we found that binding of IGF 1 , IGF 2 , and insulin to mac 25 or connective tissue growth factor was below the detection limit of the biosensor instrument . . ^^^
Interacting proteins: Q16270 and P01344	Pubmed	SVM Score :0.0
A few differentially expressed genes , including collagen type 18 alpha 1 , insulin like growth factor 2 ( IGF 2 ) , discordin domain tyrosine kinase 2 , NAD ( P ) H menadione oxidoreductase , homolog 2 of Drosophila large disk , and cyclin dependent kinase 6 were highly expressed in DPSCs , whereas insulin like growth factor binding protein 7 ( IGFBP 7 ) , and collagen type 1 alpha 2 were more highly expressed in BMSSCs . ^^^ The protein expression patterns for both IGF 2 and IGFBP 7 correlated with the differential mRNA levels seen between DPSCs and BMSSCs . ^^^
Interacting proteins: Q16270 and P01344	Pubmed	SVM Score :0.0
Altered expression levels of several genes identified in this study have been previously noted in meningiomas ( eg , growth hormone receptor , IGFBP 7 , endothelin receptor A , IGF 2 ) . ^^^
Interacting proteins: Q16270 and P01344	Pubmed	SVM Score :0.0
IGFBP related protein 1 ( IGFBP rP 1 ) , the product of the mac 25 gene , binds IGF 1 , IGF 2 , and insulin , and we postulated that glucocorticoids regulate IGFBP rP 1 synthesis in osteoblasts . ^^^
Interacting proteins: Q16270 and P01344	Pubmed	SVM Score :0.0
IGFBP related protein 1 ( IGFBP RP 1 ) , the product of the mac 25 gene , binds IGF 1 , IGF 2 , and insulin . ^^^ GH , insulin , bone morphogenetic protein 2 , fibroblast growth factor 2 , platelet derived growth factor BB , IGF 1 , and IGF 2 did not modify mac25 / IGFBP RP 1 expression , whereas transforming growth factor beta 1 was modestly stimulatory . ^^^
Interacting proteins: Q16270 and P01344	Pubmed	SVM Score :0.0
In random normal human adult sera ( n = 37 ) , the median IGFBP rP 1 was 21 . 0 micro g / liter , and values did not correlate with levels of IGF 1 ( r = 0 . 085 , P = 0 . 61 ) , IGF 2 ( r = 0 . 051 , P = 0 . 75 ) , or IGFBP 3 ( r = 0 . 061 , P = 0 . 74 ) . ^^^
Interacting proteins: Q16270 and P01344	Pubmed	SVM Score :0.0
Binding of 125I IGF 1 and 125I IGF 2 to rh mac 25 was demonstrated by Western ligand blotting after nondenaturing polyacrylamide gel electrophoresis and by affinity cross linking with as little as 2 nM rh mac 25 . ^^^ Specificity of rh mac 25 binding to 125I IGFs was demonstrated by competition for rh mac 25 binding with unlabeled IGFs , but not with [ QAYLL ] IGF 2 analog , which has 100 fold less affinity for IGFBPs . ^^^ In comparison with IGFBP 3 , rh mac 25 has at least a 5 6 fold lower affinity for IGF 1 and 20 25 fold lower affinity for IGF 2 . mac 25 mRNA was detectable in a wide range of normal human tissues , with decreased expression in breast , prostate , colon , and lung cancer cell lines . ^^^
Interacting proteins: Q16270 and P01344	Pubmed	SVM Score :0.0
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Interacting proteins: Q16270 and P01344	Pubmed	SVM Score :0.0
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Interacting proteins: Q16270 and P01344	Pubmed	SVM Score :0.0
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Interacting proteins: Q16270 and P01344	Pubmed	SVM Score :0.0
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Interacting proteins: Q16270 and P01344	Pubmed	SVM Score :0.0
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Interacting proteins: Q16270 and P01344	Pubmed	SVM Score :0.0
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Interacting proteins: Q16270 and P01344	Pubmed	SVM Score :0.0
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